The orifice reducer in the center of the bottle neck is to remain in place. The reducer helps to avoid the loss of tincture due to spillagge and also stops outside artifacts from contaminating the tinctures. The syringe provided in the box fits directly in the center of the orifice reducer. With the first few administrations, there will be a snug fit for the syringe into the reducer but that is what we want to avoid loss of the product.
To draw out the tincture, please put the syringe into the center of the orifice reducer, turn the bottle upside down (this allows gravity to help fill the syringe), and draw out the precise dose amount for your patient.